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Reliable Quality alpha-Cyclopentylmandelic acid 427-49-6 Hot Sale with Chinese Manufacturer

  • Molecular Formula: C13H16O3
  • Molecular Weight: 220.268
  • Appearance/Colour: white to beige powder 
  • Vapor Pressure: 5.73E-07mmHg at 25°C 
  • Melting Point: 144-150 °C 
  • Boiling Point: 395.6 °C at 760 mmHg 
  • PKA: 3.53±0.25(Predicted) 
  • Flash Point: 207.2 °C 
  • PSA: 57.53000 
  • Density: 1.247 g/cm3 
  • LogP: 2.14900 

alpha-Cyclopentylmandelic acid(Cas 427-49-6) Usage

InChI:InChI=1/C13H16O3/c14-12(15)13(16,11-8-4-5-9-11)10-6-2-1-3-7-10/h1-3,6-7,11,16H,4-5,8-9H2,(H,14,15)/p-1/t13-/m0/s1

427-49-6 Relevant articles

-

Dobrina,Joffe

, (1977)

-

GLYCOPYRRONIUM FATTY ACID SALTS AND METHODS OF MAKING SAME

-

Paragraph 59, (2017/01/02)

Novel glycopyrronium fatty acid salts ha...

Carry over of impurities: A detailed exemplification for glycopyrrolate (NVA237)

Allmendinger, Thomas,Bixel, Dominique,Clarke, Adrian,Di Geronimo, Laura,Fredy, Jean-Wilfried,Manz, Marco,Gavioli, Elena,Wicky, Regine,Schneider, Martin,Stauffert, Fabien J.,Tibi, Markus,Valentekovic, Darko

supporting information, p. 1754 - 1769 (2013/01/15)

The original synthesis of glycopyrrolate...

Stereoisomers of N-substituted soft anticholinergics and their zwitterionic metabolite based on glycopyrrolate - Syntheses and pharmacological evaluations

Wu,Wu,Mori,Buchwald,Bodor, Nicholas

experimental part, p. 200 - 209 (2009/04/07)

Purpose. In this study, isomers of two N...

Synthesis and optimization of novel and selective muscarinic M3 receptor antagonists

Kumar, Naresh,Kaur, Kirandeep,Aeron, Shelly,Dharmarajan, Sankaranarayanan,Silamkoti, Arun D.V.,Mehta, Anita,Gupta, Suman,Chugh, Anita,Gupta, Jang B.,Salman, Mohammad,Palle, Venkata P.,Cliffe, Ian A.

, p. 5256 - 5260 (2008/02/11)

A series of constrained piperidine analo...

427-49-6 Process route

Cyclozil chloromethacryloyloxymethylate
74240-38-3

Cyclozil chloromethacryloyloxymethylate

formaldehyd
50-00-0,30525-89-4,61233-19-0

formaldehyd

2-(N,N-dimethylamino)ethanol
108-01-0

2-(N,N-dimethylamino)ethanol

poly(methacrylic acid)
79-41-4,25087-26-7,50867-57-7

poly(methacrylic acid)

2-cyclopentyl-2-hydroxy-2-phenylacetic acid
427-49-6

2-cyclopentyl-2-hydroxy-2-phenylacetic acid

Conditions
Conditions Yield
With potassium chloride; In methanol; at 24.9 ℃; Rate constant; Kinetics; Mechanism; different pH values from 298-323 K, different ion strength of KCl solution;
glycopyrronium bromide
596-51-0,129784-12-9,201667-20-1,53808-86-9,58493-54-2

glycopyrronium bromide

3-hydroxy-1,1-dimethyl pyrrolidinium bromide
51052-74-5

3-hydroxy-1,1-dimethyl pyrrolidinium bromide

2-cyclopentyl-2-hydroxy-2-phenylacetic acid
427-49-6

2-cyclopentyl-2-hydroxy-2-phenylacetic acid

Conditions
Conditions Yield
With sodium hydroxide; In water; at 20 ℃;
92%
3.87 g

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    2-cyclopentyl-2-hydroxy-2-phenylacetic acid ethyl ester

427-49-6 Downstream products

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    (+/-)-J 104129

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    (1α, 5α ,6α)-6-N-(3-azabicyclo[3.1.0] hexyl-3-benzyl)-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

  • 712356-39-3
    712356-39-3

    (1α, 5α, 6α)-6-N-(3-azabicyclo-[3.1.0] hexyl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide

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